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Starvation and infection: The role of sickness-associated anorexia in metabolic adaptation during acute infection

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To Immunity and Beyond
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Dr. Barbara Kronsteiner-Dobramysl discusses a recent Metabolism article: ‘Starvation and infection: The role of sickness-associated anorexia in metabolic adaptation during acute infection’.
This episode discusses the following article: Jindal, J, Hill, J, Harte, J, Dunachie, S, and Barbara Kronsteiner, B, Starvation and infection: The role of sickness-associated anorexia in metabolic adaptation during acute infection. Metabolism 161 (December 2024). https://doi.org/10.1016/j.metabol.2024.156035
Barbara would like to specifically thank Ms. Jessy Jindal for the initial idea for this review. As part of her medical studies at the University of Oxford she wrote an essay about starvation and infection which inspired this publication. This work matured over several years and was shaped by all the co-authors and valuable input from reviewers and the editor until it reached its final version that is published now. We hope it is of interest to many and sparks conversation and new ideas for studies in this area.

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Professor Omer Dusk discusses a bioRxiv pre-print: ‘Optimising CAR-T cell sensitivity by engineering matched extracellular sizes between CAR/antigen and CD2/CD58 adhesion complexes’.
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To Immunity and Beyond

Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype

Dr Kirsty McHugh and Dr Carolyn Nielsen discuss a recent Cell article: ‘Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype’.
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Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/
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Episode Information

Series
To Immunity and Beyond
People
Kronsteiner-Dobramysl
Paul Klenerman
Keywords
immunometabolism
ketogenesis
gdf15
leptin
Department: Oxford Immunology Network
Date Added: 27/02/2025
Duration:

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